Controlled-release hydromorphone and risk of infection in adults: a systematic review

Lit review
par
Tricco, Andrea C. et al

Date de publication

2023

Géographie

International

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

Preliminary evidence suggests that people who inject drugs (PWID) may be at an increased risk of developing infective endocarditis (IE), hepatitis C virus (HCV) infection, and/or human immunodeficiency virus (HIV) infection from hydromorphone controlled-release formulation.

Constatations/points à retenir

One retrospective cohort study found an association between controlled-release hydromorphone and IE, whereas a case–control study found no evidence of an association. One retrospective cohort study found an association between the number of hydromorphone controlled-release prescriptions and prevalence of HCV. None of the studies specifically reported on associations with HIV.

La conception ou méthodologie de recherche

Lit review (5 studies included)

Mots clés

Safer supply
About PWUD
Injecting drugs
Outcomes