Maternal Opioid Use Disorder and the Risk of Postneonatal Infant Mortality

Original research
par
Grossarth, Sarah et al

Date de publication

2023

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

To characterize the risk of postneonatal infant mortality among infants with a neonatal opioid withdrawal syndrome (NOWS) diagnosis or born to individuals with opioid use disorder (OUD).

Constatations/points à retenir

The study team observed 1317 postneonatal infant deaths and incidence rates of 3.47 (OUD negative/NOWS negative, 375 718), 8.41 (OUD positive/NOWS positive, 4922); 8.95 (OUD positive/NOWS negative, 7196), and 9.25 (OUD negative/NOWS positive, 2239) per 1000 person-years. After adjustment, the risk of postneonatal death was elevated for all groups, relative to the unexposed: OUD positive/NOWS positive, OUD positive/NOWS negative, and OUD negative/NOWS positive.

La conception ou méthodologie de recherche

Retrospective cohort study (n=390 075)

Mots clés

Mortality
Parents/caregivers
Outcomes