Clinical Management of Psychostimulant Withdrawal: Review of the Evidence

Lit review
by
Li, Michael J. & Steven J. Shoptaw

Release Date

2022

Geography

USA

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

This review of clinical research reports the evidence regarding biomedical and behavioral treatments for psychostimulant withdrawal symptoms.

Findings/Key points

Potential efficacy for MA withdrawal is noted for a few medications (mirtazapine, naltrexone, bupropion) and repetitive transcranial magnetic stimulation during acute (first week), early protracted (weeks 2-4) and late protracted (>4 weeks) withdrawal phases. Topiramate shows mixed evidence of efficacy for cocaine withdrawal. In general, there is inconsistent signal for biomedical and behavioral treatments on MA and cocaine withdrawal.

Keywords

Withdrawal
Stimulants
Clinical guidance