Lit review
by
Klimas, Jan et al
Release Date
2021
Geography
International
Language of Resource
English
Full Text Available
Yes
Open Access / OK to Reproduce
Yes
Peer Reviewed
Yes
Objective
This rapid review sought to summarize the retention rates reported by randomized controlled trials (RCTs) and controlled observational study designs that compared methadone to buprenorphine (or buprenorphine-naloxone).
Findings/Key points
The mean weighted retention rate and 95% confidence interval (CI) for studies with follow-up periods between 4 and 6 months using buprenorphine was 57.3% (95% CI = 53.5%, 61.1%) and using methadone was 65.5% (95% CI = 60.5%, 70.5%).
Design/methods
3 observational studies and 10 RCTs met inclusion criteria
Keywords
Substitution/OAT
Outcomes
About PWUD
