Safety profile of injectable hydromorphone and diacetylmorphine for long-term severe opioid use disorder

Slide deck
by
Oviedo-Joekes, Eugenia

Release Date

2018

Geography

Canada

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

No

Peer Reviewed

No

Objective

The aim of this presentation is to examine the safety profile of injectable
hydromorphone and diacetylmorphine by analyzing rates of adverse
events (AEs) in the SALOME study and exploring if they were
associated with dose and patterns of treatment attendance.

Findings/Key points

When injectable hydromorphone and diacetylmorphine are individually dosed and monitored, their opioid-related side effects, including potential fatal overdoses, are safely mitigated and treated by health care providers. Related adverse events did not lead to more missed treatment days and the dose prescribed does not seem to play a direct or sole role.

Keywords

Safer supply
Evidence base
Overdose
Outcomes