Welcome to our searchable resource and literature collection on safer supply and related topics.

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The present meta-analysis was conducted to evaluate the efficacy and safety of tramadol in the treatment of opioid withdrawal.

Original research | 2023
Withdrawal, Clinical guidance

We assessed whether Canada’s cannabis legalization was associated with changes in adult police-reported cannabis-related, property, or violent criminal incidents.

Original research | 2023
Crime, Decriminalization/legalization, Policy/Regulatory, Justice system/law enforcement
Commentary | 2023
Harm reduction, Policy/Regulatory

We identified longitudinal substance use profiles in young Black American men and examined their links to childhood adversity, racial discrimination and young adult problem substance use and mental

Original research | 2023
Equity, About PWUD, Youth, Sex/Gender

Gender and sexual minority/minoritized groups are at a higher risk of substance misuse and related harm compared to the rest of the population.

Original research | 2023
About PWUD, 2SLGBTQI+, Stigma, Barriers and enablers

We assessed the prevalence and risk of mortality for concurrent alcohol use disorder (AUD) among people with opioid use disorder (PWOUD) who accessed opioid agonist therapy (OAT) in British Columbi

Original research | 2023
Mortality, Substitution/OAT, About PWUD

This paper analyses a translation of an Italian Renaissance Latin monograph’s key content elements and its place in the history of the concept of addiction.

Commentary | 2023
About PWUD
Book | 2023
Peer/PWLLE program involvement
Video | 2022
About PWUD, Sex/Gender , Parents/caregivers
Video | 2023
Harm reduction, Policy/Regulatory, Barriers and enablers
Commentary | 2023
Parents/caregivers, Youth, Stigma, Barriers and enablers

Given the widespread presence of fentanyl in the drug supply, research is needed to understand who is at greatest risk for concurrent medication for opioid use disorder (MOUD) and drug use and the

Original research | 2023
About PWUD, Substitution/OAT, Transitions in care/treatment

Here, we examined the neuropharmacology of structurally distinct non-fentanyl NSOs, including U-47700, isotonitazene, brorphine, and N-desethyl isotonitazene, as compared to morphine and fentanyl.

Original research | 2023
Drug checking, Illegal drugs

We examine if the shift to the illicit market after the reformulation of OxyContin in the U.S.

Original research | 2023
Overdose, Mortality, Policy/Regulatory, Outcomes

This cross-sectional study investigates the impact of benzodiazepine (BZD) use in opioid agonist treatment (OAT) patients on their quality of life (QoL).

Original research | 2023
About PWUD, Mental health

We conducted a rapid review of qualitative and quantitative peer-reviewed and grey literature publications that describe the clinical outcomes of SOS programs, as well as the perceptions of clients

Lit review | 2023
Evidence base, Safer supply

We investigated the association between fentanyl injection frequency and sharing of injection equipment among people who inject drugs

Original research | 2022
Injecting drugs, About PWUD, Harm reduction

We measured the prevalence of mono-use versus polysubstance use (PSU) in those who used substances in the past year, those with at least two symptoms of an SUD and in those who received treatment f

Original research | 2023
About PWUD

We sought to examine linkages between socioeconomic marginalization and non-fatal overdose risk in a community deeply affected by the ongoing drug poisoning crisis.

Original research | 2023
Overdose, About PWUD, Poverty, Housing, Justice system/law enforcement

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