Dose Tapering, Increases, and Discontinuity among Patients on Long-Term High-Dose Opioid Therapy in the United States, 2017-2019

Original research
par
Nataraj, Nisha et al

Date de publication

2022

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

To examine potentially unsafe tapering and discontinuation among dosage changes in opioid prescriptions dispensed to US patients on high-dose long-term opioid therapy.

Constatations/points à retenir

Half of patients on high-dose long-term opioid therapy had daily dosages tapered. Many patients experienced dosage reductions exceeding recommended rates. Rapid tapers were more likely among patients with baseline daily dosages ≥150 MME.

La conception ou méthodologie de recherche

Longitudinal observational study (n=595,078)

Mots clés

About PWUD
Withdrawal