Relative effectiveness of medications for opioid-related disorders: A systematic review and network meta-analysis of randomized controlled trials

Lit review
par
Lim, Jihoon et al

Date de publication

2022

Géographie

International

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

Our objective was to unify findings from different healthcare practices and generate evidence to strengthen clinical treatment protocols for the most widely prescribed medications for opioid-use disorders.

Constatations/points à retenir

Methadone was the highest ranked intervention (Surface Under the Cumulative Ranking in the network with control being the lowest. Methadone was superior to buprenorphine for treatment retention and buprenorphine superior to naltrexone.

La conception ou méthodologie de recherche

Meta-analysis

Mots clés

Substitution/OAT