Opium tincture versus methadone for opioid agonist treatment: A randomized controlled trial

Original research
par
Nikoo, Mohammadali et al

Date de publication

2022

Géographie

Iran

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

To test if opium tincture (OT) was non-inferior to methadone in retaining participants in opioid agonist treatment (OAT).

Constatations/points à retenir

While this study could not conclude the non-inferiority of opium tincture (OT) to methadone for retaining patients in opioid agonist treatment, OT retained 60% of participants to end of follow up (85 days) and was superior to methadone in reducing self-reported opioid use outside treatment.

La conception ou méthodologie de recherche

A phase III, multicentre, parallel group, non-inferiority, double-blind randomized controlled trial with an allocation ratio of 1:1

Mots clés

Substitution/OAT
About PWUD