Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder

Original research
par
Thakrar, Ashish P. et al

Date de publication

2023

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

Patients with opioid use disorder (OUD) frequently leave the hospital as patient directed discharges (PDDs) because of untreated withdrawal and pain. Short-acting opioids can complement methadone, buprenorphine, and non-opioid adjuvants for withdrawal and pain, however little evidence exists for this approach. We described the safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with OUD at an academic hospital in Philadelphia, PA.

Constatations/points à retenir

Pilot implementation of sOAT was safe. Compared to prior admissions in the same cohort, the patient directed discharge rate was lower, length of stay for patient directed discharges was longer, and more patients were discharged on buprenorphine or methadone and with naloxone, however efficacy for these secondary outcomes remains to be established.

La conception ou méthodologie de recherche

Pilot sOAT protocol (n=23)

Mots clés

Safer supply
Substitution/OAT
Hospitals
Outcomes