Evaluation of heroin maintenance in controlled trial

Original research
by
Hartnoll, R L et al

Release Date

1980

Geography

UK

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

Assess injectable heroin vs. oral methadone

Findings/Key points

Heroin group: maintain status quo, majority continue to inject regularly, supplement prescription with other sources, and continue intermediate level of involvement with drug subculture and criminal activity.

Methadone group: confrontational because wouldn’t prescribe heroin, higher abstinence rate, but also greater dependence on illegal sources of drugs for those continue to inject. More likely to be arrested.

No difference between groups in employment, health, consumption of non-opiate drugs. Methadone had a significantly greater drop out from regular treatment.

Design/methods

n=96 RCT or heroin or methadone; followed for 12 months

Keywords

Evidence base
Outcomes
Legal system/law enforcement
Substitution/OAT
Social benefits