Prescribed opioid analgesics in early pregnancy and the risk of congenital anomalies: a population-based cohort study

Original research
by
Bowie, Alexa C. et al

Release Date

2022

Geography

Canada

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

Yes

Peer Reviewed

Yes

Objective

We sought to further quantify the risk of anomalies after opioid analgesic exposure during the first trimester in a population-based cohort study.

Findings/Key points

Although the absolute risk of congenital anomalies was low, our findings add to accumulating data that suggest a small increased risk of some organ system anomalies and specific anomalies with first trimester exposure to opioid analgesics.

Design/methods

Administrative health data

Keywords

Sex/Gender
Illegal drugs
About PWUD
Parents/caregivers