Original research
by
Bozinoff, Nikki et al
Release Date
2022
Geography
Canada
Language of Resource
English
Full Text Available
Yes
Open Access / OK to Reproduce
Yes
Peer Reviewed
Yes
Objective
To understand what prescribing characteristics are associated with opioid overdose following buprenorphine taper.
Findings/Key points
In this retrospective cohort study, buprenorphine tapers undertaken after at least 1 year of therapy, a slower rate of taper, and a lower percentage of days during which the dose was decreasing were associated with a significantly lower risk of opioid overdose, regardless of taper duration. These findings underscore the importance of a carefully planned taper and could contribute to reduction in opioid-related overdose death.
Design/methods
Population-based retrospective cohort study using linked administrative health data
Keywords
Substitution/OAT
Overdose
Transitions in care/treatment
About PWUD
Clinical guidance
