Original research
par
West, Robert et al
Date de publication
2009
Géographie
USA
Langue de la ressource
English
Texte disponible en version intégrale
Non
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
Morphine preparations are known to have small amounts of codeine as an impurity estimated to be about 0.04%
Constatations/points à retenir
The finding of codeine was ascribed to the manufacturing process of the morphine medications. Clinicians and laboratories testing urine for drugs should be aware of this possibility.
La conception ou méthodologie de recherche
In a population of 535 pain patients prescribed morphine, Kadian, MS Contin, and/or Avinza, the investigators observed 24 samples that contained codeine >20 ng/mL.
Mots clés
Drug checking
Substitution/OAT
