Alleviation of Opioid Withdrawal by Cannabis and Delta-9-Tetrahydrocannabinol: A Systematic Review of Observational and Experimental Human Studies

Lit review
par
De Aquino, Joao P. et al

Date de publication

2022

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

The therapeutic benefits of cannabinoids remain unclear, especially when weighted against their adverse effects.

Constatations/points à retenir

Although there is preliminary evidence that cannabis and its main psychoactive constituent, THC, may alleviate opioid withdrawal, these effects are likely to have a narrow therapeutic window. Further, the potential of cannabinoids to alleviate opioid withdrawal is determined by complex interactions between patient characteristics and pharmacological factors.

Mots clés

Withdrawal
Clinical guidance