Associations of Methadone and BUP/NX Dose Titration Patterns With Retention in Treatment and Opioid Use in Individuals With Prescription-Type Opioid Use Disorder: Secondary Analysis of the OPTIMA Study

Original research

par

Bakouni, Hamzah et al

Date de publication

2024

Géographie

Canada

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

We describe methadone and BUP/NX titration patterns and their associations with treatment outcomes among individuals with a prescription-type opioid use disorder (OUD).

Constatations/points à retenir

Sustained methadone dose titration, when indicated, may help increase retention, whereas faster dose titration for methadone may help decrease opioid use.

La conception ou méthodologie de recherche

We used data from a 24-week open-label, multicenter randomized controlled trial, including N = 167 participants aged 18–64 years old with prescription-type OUD who received at least a first dose of treatment

doi.org

Mots clés

Substitution/OAT

Outcomes